| Customization: | Available |
|---|---|
| CAS No.: | 38183-03-8 |
| Formula: | C26h45no6s |
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Description:
Taurodeoxycholic acid is a bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. Bile acids are steroid acids found predominantly in the bile of mammals. The distinction between different bile acids is minute, depending only on the presence or absence of hydroxyl groups on positions 3, 7, and 12. Bile acids are physiological detergents that facilitate excretion, absorption, and transport of fats and sterols in the intestine and liver. Bile acids are also steroidal amphipathic molecules derived from the catabolism of cholesterol. They modulate bile flow and lipid secretion, are essential for the absorption of dietary fats and vitamins, and have been implicated in the regulation of all the key enzymes involved in cholesterol homeostasis. Bile acids recirculate through the liver, bile ducts, small intestine and portal vein to form an enterohepatic circuit. They exist as anions at physiological pH and, consequently, require a carrier for transport across the membranes of the enterohepatic tissues. The unique detergent properties of bile acids are essential for the digestion and intestinal absorption of hydrophobic nutrients. Bile acids have potent toxic properties (e.g. membrane disruption) and there are a plethora of mechanisms to limit their accumulation in blood and tissues Taurodeoxycholic acid can be found in Escherichia.
Application:
TUDCA (which has the trade name Tudcabil) is currently classified as a 'supplement' for certain liver disorders but has shown to be useful in treating amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, and Huntington's disease.
| tems | Standard | |
| Description | White or off-white powder | |
| Melting point | 200ºC~204ºC | |
| Specific optical rotation | +58.0°~+62.0° | |
| Identification | A | Comparable IR absorption with the referance |
| B | The spot is similar in position,color and size with the referance spot. | |
| C | Blue-green precipitate occurs | |
| Related substance(TLC) | Lithocholic Acid≤0.1% | |
| Heavy metals | ≤10ppm | |
| Chloride | ≤0.02% | |
| Sulphate | ≤0.05% | |
| Loss on drying | ≤1.0% | |
| Residue on ignition | ≤0.1% | |
| Assay(On dried basis) | 99.0%~101.0% | |
Packaging:
Shipping:
Q1:May I get one simple before placing order?
For those high value products, you just need to freight and certain productcost. When we both cooperate for some times or when you are our VIPcustomer, free sample will be offered when you need.
Q2:Which payment is available for your company?
Re: T/T, L/C trade insurance. You can choose the one which isconvenient for you.
Q3.:How and when can l get my goods after payment?
Re: For small quantity products, they will be delivered to you byinternational courier(DHL, FedEx, TNT etc.) or by air. Usually it will cost3-5days that you can get the goods after delivery.For large quantityproducts,shipping by see is worthwhile.lt will cost days to weeks to come toyour destination port, which depends on where the port is.
Q4: Is there any possible to use my appointed label or package?
Re: Yes. lf needed, we'd like to use label or package according to yourrequirement.
Q5: How can you guarantee the goods you offer is qualified?
Re: We always believe honesty and responsibility are basis of onecompany, so whatever products we provide for you all are qualified. We willhave goods tested and provide COA before delivery for sure.
After Sales Service:
NO.1.Our company guarantes that the products that leave the factory are produced and inspected accrding to the relevant national standards and the ungualitfed productswll never leave the factory. Guarantee the strict implementation and fulfilment ofproduct quality, and strictly implement relevant regulations on product afer-salesservice.
NO.2. the customer raises objection to the quality ofou company's products, we promises to respond within 24 hours afer reciving the user's objection Ifthe quality ofour company's products does not meet the promise, we are willing to refund the payment.
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